Article
No linkage or association of five polymorphisms in the interleukin-4 receptor alpha gene with atopic asthma in Italian families.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Oct 2003
Migliaccio C, Patuzzo C, Malerba G, Trabetti E, Galavotti R, Pescollderung L, Boner A L, Pignatti P F
Abstract excerpt
The literature contains conflicting reports on the association of common variants of the interleukin (IL)-4 receptor alpha (IL4RA) gene with atopic asthma. The purpose of the present study was to investigate the linkage and association of several gene polymorphisms with atopic asthma in a large series of well-characterized individuals. Analysis of five polymorphisms (I50V, E375A, C406R, S478P and Q551R) of the...
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