Article
Listeria monocytogenes internalins are highly diverse and evolved by recombination and positive selection.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Sept 2006
Tsai Yeu-Harn L, Orsi Renato H, Nightingale Kendra K, Wiedmann Martin
Abstract excerpt
To probe the evolution of internalins with confirmed or suspected roles in Listeria monocytogenes virulence we sequenced the full inlB, inlC2, inlC, inlD, inlE, inlF, inlG, and inlH ORFs from 40 L. monocytogenes isolated from human (n=10) and animal (n=10) clinical cases, foods (n=10), and the natural environment (n=10). inlB and inlE were present in all isolates, representing 26 and 20 alleles, respectively....
Topics
- Alleles
- Animals
- Bacterial Proteins
- Base Composition
- Base Sequence
- Evolution, Molecular
- Genetic Variation
- Genome, Bacterial
- Humans
- Listeria monocytogenes
- Models, Genetic
- Molecular Sequence Data
- Phylogeny
- Recombination, Genetic