Article
Human hepatitis B virus mutants: significance of molecular changes.
FEBS letters - 25 Jun 1999
Chen W N, Oon C J
Abstract excerpt
Human hepatitis B virus, the leading pathogen for hepatitis B, is a compact DNA virus with viral genes that largely overlap. An increasing number of mutations have emerged following human interventions such as vaccination and anti-viral therapy. While vaccine escape mutants are characterized by mutations on the antigenic hepatitis B surface antigen, those carrying mutations in other viral proteins are either...
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