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Article

Multiple single-nucleotide polymorphisms in the methylenetetrahydrofolate reductase and its truncated pseudogene of 23 inbred strains of mice.

Biochemical and biophysical research communications - 12 Dec 2003

Takeya Chiaki, Esumi Mariko, Shiroishi Toshihiko, Hishida Ryohei, Yamamoto Tatsuo

Abstract excerpt

Reduced 5,10-methylenetetrahydrofolate reductase (MTHFR) results in a number of human diseases. To find a model mouse sensitive to these diseases, we analyzed single-nucleotide polymorphisms (SNPs) of the mouse Mthfr using 23 phylogenetically distant strains of mouse. We found five SNPs: two nons...

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Share to Enzyme Activation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Sequence Homology, Amino Acid

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Source

Identifiers

PMID: 14637162
DOI: 10.1016/j.bbrc.2003.10.139

Genes

CAST
MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14637162-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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