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Article

Loss of heterozygosity in tuberous sclerosis hamartomas.

1 Nov 1996

Abstract excerpt

We have previously described in tuberous sclerosis (TSC) hamartomas the phenomenon of loss of heterozygosity (LOH) for DNA markers in the region of both the TSC2 gene on chromosome 16p13.3 and the TSC1 gene on 9q34. We now describe the spectrum of LOH in 51 TSC hamartomas from 34 cases of TSC. DNA was extracted from leucocytes or normal paraffin embedded tissue, and from frozen paraffin embedded hamartoma tissue...

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Identifiers

PMID: 8950679
DOI: 10.1136/jmg.33.11.962

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Loss of heterozygosity in tuberous sclerosis hamartomas.PMID 8950679Read ↗

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Loss of heterozygosity on chromosome 16p13.3 in hamartomas from tuberous sclerosis patients.Semantic proximity Read ↗

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