Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lipoprotein receptors and a disabled family cytoplasmic adaptor protein regulate EGL-17/FGF export in C. elegans.

Genes & development - 15 Nov 2003

Kamikura Darren M, Cooper Jonathan A

Abstract excerpt

Growth factors and morphogens need to be secreted to act on distant cells during development and in response to injury. Here, we report evidence that efficient export of a fibroblast growth factor (FGF), EGL-17, from the Caenorhabditis elegans developing vulva requires the lipoprotein receptor-related proteins Ce-LRP-1 and Ce-LRP-2 and a cytoplasmic adaptor protein, Ce-DAB-1 (Disabled). Lipoprotein receptors are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Vesicular Transport
Share to Apoptosis Regulatory Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibroblast Growth Factors

Share to Golgi Apparatus

Share to Precipitin Tests

Share to Receptors, Lipoprotein

Share to Subcellular Fractions

Source

Open in PubMed Open full text

Identifiers

PMID: 14630941
DOI: 10.1101/gad.1136103
PMCID: PMC280628

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lipoprotein receptors and a disabled family cytoplasmic adaptor protein regulate EGL-17/FGF export in C. elegans.PMID 14630941Read ↗

C. elegans Disabled is required for cell-type specific endocytosis and is essential in animals lacking the AP-3 adaptor complex.Semantic proximity Read ↗

Clathrin interaction and subcellular localization of Ce-DAB-1, an adaptor for protein secretion in Caenorhabditis elegans.Semantic proximity Read ↗

LIN-12/Notch trafficking and regulation of DSL ligand activity during vulval induction in Caenorhabditis elegans.Semantic proximity Read ↗

Boca, an endoplasmic reticulum protein required for wingless signaling and trafficking of LDL receptor family members in Drosophila.Semantic proximity Read ↗

The engulfment receptor CED-1/MEGF10 activates the GPCR LAT-1/ADGRL3 for apoptotic cell degradationSemantic proximity Read ↗

FOS-1 promotes basement-membrane removal during anchor-cell invasion in C. elegans.Semantic proximity Read ↗

N-Myc downstream regulated gene 1b is a regulator of cell adhesion during early muscle developmentSemantic proximity Read ↗

LRBA, a BEACH protein mutated in human immune deficiency, is widely expressed in epithelia, exocrine and endocrine glands, and neurons.Semantic proximity Read ↗

A developmental gene regulatory network for invasive differentiation of the <i>C. elegans</i> anchor cellSemantic proximity Read ↗

The lateral signal for LIN-12/Notch in C. elegans vulval development comprises redundant secreted and transmembrane DSL proteins.Semantic proximity Read ↗

IGDB-2, an Ig/FNIII protein, binds the ion channel LGC-34 and controls sensory compartment morphogenesis in C. elegans.Semantic proximity Read ↗

The Rab GTPase activating protein TBC-2 regulates endosomal localization of DAF-16 FOXO and lifespanSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.