Article
Specific interaction between SNAREs and epsin N-terminal homology (ENTH) domains of epsin-related proteins in trans-Golgi network to endosome transport.
The Journal of biological chemistry - 6 Feb 2004
Chidambaram Subbulakshmi, Müllers Nina, Wiederhold Katrin, Haucke Volker, von Mollard Gabriele Fischer
Abstract excerpt
SNARE proteins on transport vesicles and target membranes have important roles in vesicle targeting and fusion. Therefore, localization and activity of SNAREs have to be tightly controlled. Regulatory proteins bind to N-terminal domains of some SNAREs. vti1b is a mammalian SNARE that functions in late endosomal fusion. To investigate the role of the N terminus of vti1b we performed a yeast two-hybrid screen. The...
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