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Article

Characterization of the abnormal pancreatic development, reduced growth and infertility in Cdk4 mutant mice.

Oncogene - 20 Nov 2003

Mettus Richard V, Rane Sushil G

Abstract excerpt

Cyclin-dependent kinase 4 (Cdk4) and Cdk6, and later Cdk2, in association with their specific cyclin partners, regulate the G1 to S phase cell cycle transition of mammalian cells by phosphorylation of retinoblastoma (Rb) family proteins. Phosphorylation of Rb results in the release of S-phase spe...

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Identifiers

PMID: 14627982
DOI: 10.1038/sj.onc.1206888

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-14627982-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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