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Article

Transfer of neutralizing IgG to macaques 6 h but not 24 h after SHIV infection confers sterilizing protection: implications for HIV-1 vaccine development.

Proceedings of the National Academy of Sciences of the United States of America - 9 Dec 2003

Nishimura Yoshiaki, Igarashi Tatsuhiko, Haigwood Nancy L, Sadjadpour Reza, Donau Olivia K, Buckler Charles, Plishka Ron J, Buckler-White Alicia, Martin Malcolm A

Abstract excerpt

Passive transfer of high-titered antiviral neutralizing IgG, known to confer sterilizing immunity in pig-tailed monkeys, has been used to determine how soon after virus exposure neutralizing antibodies (NAbs) must be present to block a simian immunodeficiency virus (SIV)/HIV chimeric virus infection. Sterilizing protection was achieved in three of four macaques receiving neutralizing IgG 6 h after intravenous...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 14627745
DOI: 10.1073/pnas.2436476100
PMCID: PMC299920

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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