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Article

Accommodation of a highly symmetric core within a symmetric protein superfold.

Protein science : a publication of the Protein Society - 1 Dec 2003

Brych Stephen R, Kim Jaewon, Logan Timothy M, Blaber Michael

Abstract excerpt

An alternative core packing group, involving a set of five positions, has been introduced into human acidic FGF-1. This alternative group was designed so as to constrain the primary structure within the core region to the same threefold symmetry present in the tertiary structure of the protein fold (the beta-trefoil superfold). The alternative core is essentially indistinguishable from the WT core with regard to...

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Identifiers

PMID: 14627732
DOI: 10.1110/ps.03374903
PMCID: PMC2366980

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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