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Article

No association of tumor necrosis factor alpha gene polymorphisms with schizophrenia or response to clozapine.

Schizophrenia research - 1 Dec 2003

Tsai Shih-Jen, Hong Chen-Jee, Yu Younger W-Y, Lin Ching-Hua, Liu Ling-Ling

Abstract excerpt

Tumor necrosis factor alpha (TNF-alpha), a potent immunomodulator and proinflammatory cytokine, has been implicated in schizophrenia pathogenesis and clozapine response. Two studies have established an association between schizophrenia and the TNF-alpha gene -308G/A polymorphism; however, both increased and decreased -308A allele frequency have been reported in two analogous investigations. The present study...

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Identifiers

PMID: 14623371
DOI: 10.1016/s0920-9964(02)00531-5

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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No association between the G308A polymorphism of the tumor necrosis factor-alpha gene and schizophrenia.Semantic proximity Read ↗

Tumor necrosis factor-alpha gene polymorphism at position -308 and schizophrenia in the Korean population.Semantic proximity Read ↗

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