Article
In vivo characterisation of the human UCP3 gene minimal promoter in mice tibialis anterior muscles.
Biochemical and biophysical research communications - 21 Nov 2003
Riquet Franck B, Rodriguez Marianne, Guigal Nolwen, Dromaint Sandra, Naime Isabelle, Boutin Jean A, Galizzi Jean-Pierre
Abstract excerpt
Transcriptional mechanisms controlling human UCP3 gene expression in skeletal muscle remain poorly understood. Experiments based on plasmid electrotransfer into tibialis anterior muscle of C57/BL6 male mice were set up in order to functionally analyze the hUCP3 gene promoter. These transfection experiments showed that a 6300 bp region upstream of the transcription initiation site was sufficient to mediate maximal...
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