Article
In vitro identification of two adherence factors required for in vivo virulence of Pseudomonas fluorescens.
Microbes and infection - 1 Nov 2003
de Lima Pimenta Andréa, Di Martino Patrick, Le Bouder Emmanuel, Hulen Christian, Blight Mark A
Abstract excerpt
By enriching a random transposon insertion bank of Pseudomonas fluorescens for mutants affected in their adherence to the human extracellular matrix protein fibronectin, we isolated 23 adherence minus mutants. Mutants showed a defect in their ability to develop a biofilm on an abiotic surface and were impaired for virulence when tested in an in vivo virulence model in the fruit fly, Drosophila melanogaster....
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