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Article

Drosophila as a model host for Pseudomonas aeruginosa infection.

Journal of bacteriology - 1 Feb 2001

D'Argenio D A, Gallagher L A, Berg C A, Manoil C

Abstract excerpt

Using the fruit fly Drosophila melanogaster as model host, we have identified mutants of the bacterium Pseudomonas aeruginosa with reduced virulence. Strikingly, all strains strongly impaired in fly killing also lacked twitching motility; most such strains had a mutation in pilGHIJKL chpABCDE, a gene cluster known to be required for twitching motility and potentially encoding a signal transduction system. The pil...

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Identifiers

PMID: 11157963
DOI: 10.1128/JB.183.4.1466-1471.2001
PMCID: PMC95024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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