Article
Association of genetic traits to estimated haplotypes from SNP genotypes using EM algorithm and Markov Chain Monte Carlo techniques.
Human heredity - 1 Jan 2003
Rohde K, Fürst R
Abstract excerpt
In order to find association of genetic traits to some haplotypes from closely spaced multilocus phase-unknown genotypes we use a three-stage approach. Haplotype frequencies and the most likely haplotype pair for each individual are estimated from random samples of individual or small (nuclear) family genotypes via an EM algorithm. If the most likely haplotype pair configuration of the whole sample outweighs the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
