Article
The new strategy for allele identification of the genes coding for pertussis toxin subunit S1 (ptx S1) and pertactin (prn) in Bordetella pertussis.
Journal of microbiological methods - 1 Dec 2003
Fiett Janusz, Letowska Iwona, Gniadkowski Marek, Hryniewicz Waleria
Abstract excerpt
Bordetella pertussis strains demonstrate polymorphism in toxin subunit S1 (PT S1) and pertactin (Prn), which belong to major protective antigens of the pathogen. Changes in the distribution of particular alleles of ptxS1 and prn genes in local B. pertussis populations have been proposed as possible factors influencing the vaccination effectiveness. We have developed a new methodology for the identification of the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
