Article
Bioinformatic analysis of autism positional candidate genes using biological databases and computational gene network prediction.
Genes, brain, and behavior - 1 Oct 2003
Yonan A L, Palmer A A, Smith K C, Feldman I, Lee H K, Yonan J M, Fischer S G, Pavlidis P, Gilliam T C
Abstract excerpt
Common genetic disorders are believed to arise from the combined effects of multiple inherited genetic variants acting in concert with environmental factors, such that any given DNA sequence variant may have only a marginal effect on disease outcome. As a consequence, the correlation between disease status and any given DNA marker allele in a genomewide linkage study tends to be relatively weak and the implicated...
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