Article
Targeted SNP genotyping using the TaqMan® assay.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011
Schleinitz Dorit, Distefano Johanna K, Kovacs Peter
Abstract excerpt
More than 99% of genomic DNA sequence is identical among humans, and not surprisingly, slight variations in sequence can often produce a major effect on phenotype. Sequence variants may also mediate the manner in which humans are susceptible to disease or respond to environmental factors such as bacteria, viruses, toxins, chemicals, drugs, and therapeutic interventions. Single-nucleotide polymorphisms (SNPs) are...
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