Improved phenotyping of alpha 1-antichymotrypsin (ACT) by isoelectric focusing and immunoprinting: first demonstration of a deficient protein variant in the ACT system.

doi:10.1002/elps.11501301169

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Article

Improved phenotyping of alpha 1-antichymotrypsin (ACT) by isoelectric focusing and immunoprinting: first demonstration of a deficient protein variant in the ACT system.

Electrophoresis - 1 Jan 2000

Weidinger S, Poller W, Faber J P, Schwarzfischer F

Abstract excerpt

Genetic variation of human alpha 1-antichymotrypsin (ACT) was investigated in sera using thin-layer polyacrylamide gel isoelectric focusing (pH range 4.0-6.5) followed by immunoprinting with a monospecific anti-human ACT antibody. Sialidase-treated samples showed a microheterogeneous banding patt...

Topics

Female
Genetic Variation
Humans
Immunoelectrophoresis
Isoelectric Focusing
Lung Diseases, Obstructive
Male
Pedigree
Phenotype
alpha 1-Antichymotrypsin

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