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Article

Gene frequency and partial protein characterization of an allelic variant of mannan binding protein associated with low serum concentrations.

Clinical and experimental immunology - 1 Dec 1992

Garred P, Thiel S, Madsen H O, Ryder L P, Jensenius J C, Svejgaard A

Abstract excerpt

Low plasma concentration of mannan binding protein (MBP) has been shown to be the basis for a common opsonic deficiency and suggested to be caused by a single nucleotide substitution at base 230 of exon 1 in the MBP gene. This substitution causes a replacement of glycine (codon GGC) with aspartic acid (codon GAC). Of 123 healthy Danish individuals investigated by polymerase chain reaction performed on exon 1,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 1458688
DOI: 10.1111/j.1365-2249.1992.tb05876.x
PMCID: PMC1554582

Genes

MBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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