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Article

Gene frequency and partial protein characterization of an allelic variant of mannan binding protein associated with low serum concentrations.

Clinical and experimental immunology - 1 Dec 1992

Garred P, Thiel S, Madsen H O, Ryder L P, Jensenius J C, Svejgaard A

Abstract excerpt

Low plasma concentration of mannan binding protein (MBP) has been shown to be the basis for a common opsonic deficiency and suggested to be caused by a single nucleotide substitution at base 230 of exon 1 in the MBP gene. This substitution causes a replacement of glycine (codon GGC) with aspartic...

Topics

Adult
Alleles
Base Sequence
Carrier Proteins
Collectins
Female
Gene Frequency
Genetic Variation
Genotype
Heterozygote
Homozygote
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Molecular Sequence Data

Mutation

Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 1458688
DOI: 10.1111/j.1365-2249.1992.tb05876.x
PMCID: PMC1554582

Genes

MBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1458688-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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