Article
[Analysis of the effects of mutant hairless genes in chimeric mice].
Genetika - 1 Sept 2003
Martynova M Iu, Isaev D A, Koniukhov B V
Abstract excerpt
The autosomal recessive gene hairless (hr) is responsible for the complete hairlessness in mice homozygous for this gene. Hair shedding that begins at the age of 10 days is caused by an abnormal cycle of hair follicle development disturbed at the catagen stage. This results in enhanced programmed cell death (apoptosis) and ultimately leads to the complete hair follicle destruction and shedding of all hairs by the...
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