Article
Angiotensin-converting enzyme inhibitor withdrawal and ACE gene polymorphism.
Clinical nephrology - 1 Oct 2003
Nonoguchi H, Kiyama S, Inoue H, Nakayama Y, Inoue T, Kohda Y, Machida K, Tajima A, Kitamura K, Miyoshi T, Shimada H, Shimada H, Tajiri M, Honda Y, Tanaka M, Tomita K
Abstract excerpt
AIMS: Withdrawal of angiotensin-converting enzyme (ACE) inhibitors may affect the progression of chronic renal failure and an insertion/deletion (I/D) polymorphism of the ACE gene may influence it. METHODS: We retrospectively collected patients with chronic glomerulonephritis and benign nephrosclerosis who discontinued ACE inhibitor use. The relationship between the decline of renal function after the withdrawal...
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