Article
[Association analysis of angiotensin-converting enzyme gene polymorphism with end-stage renal disease].
Nihon Ika Daigaku zasshi - 1 Apr 1998
Hashimoto K, Osono E, Iino Y, Terashi A
Abstract excerpt
BACKGROUND: Intron 16 insertion/deletion (I/D) polymorphism in the angiotensin-converting enzyme (ACE) gene may be associated with the progression of renal insufficiency in patients with renal diseases. The objective of this study was to determine whether D allele is a risk factor for the progression of the disease in end-stage renal disease (ESRD) patients. METHODS: Using PCR techniques, genetic analysis of the...
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