Article
Insertion/deletion polymorphism of the ACE gene and adherence to ACE inhibitors.
British journal of clinical pharmacology - 1 Apr 2005
Schelleman H, Klungel O H, van Duijn C M, Witteman J C M, Hofman A, de Boer A, Stricker B H Ch
Abstract excerpt
AIMS: We investigated whether the insertion/deletion (I/D) polymorphism of the ACE gene modified the adherence to ACE inhibitors as measured by the discontinuation of an ACE inhibitor, or addition of another antihypertensive drug. METHODS: This was a cohort study among 239 subjects who started ACE inhibitor therapy. A Cox proportional hazard model was used to calculate relative risk (RR). RESULTS: During...
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