Article
Functional characterization of an archaeal GroEL/GroES chaperonin system: significance of substrate encapsulation.
The Journal of biological chemistry - 9 Jan 2004
Figueiredo Luis, Klunker Daniel, Ang Debbie, Naylor Dean J, Kerner Michael J, Georgopoulos Costa, Hartl F Ulrich, Hayer-Hartl Manajit
Abstract excerpt
In all three kingdoms of life chaperonins assist the folding of a range of newly synthesized proteins. As shown recently, Archaea of the genus Methanosarcina contain both group I (GroEL/GroES) and group II (thermosome) chaperonins in the cytosol. Here we report on a detailed functional analysis of the archaeal GroEL/GroES system of Methanosarcina mazei (Mm) in comparison to its bacterial counterpart from...
Topics
- Adenosine Triphosphatases
- Ammonium Sulfate
- Archaea
- Bacteriophages
- Chaperonin 10
- Chaperonin 60
- Chaperonins
- Cytosol
- Escherichia coli
- Genetic Complementation Test
- Malate Dehydrogenase
- Methanosarcina
- Mutation