Article
Two genome-wide linkage disequilibrium screens in Scandinavian multiple sclerosis patients.
Journal of neuroimmunology - 1 Oct 2003
Harbo Hanne F, Datta Pameli, Oturai Annette, Ryder Lars P, Sawcer Stephen, Setakis Efrosini, Akesson Eva, Celius Elisabeth G, Modin Helena, Sandberg-Wollheim Magnhild, Myhr Kjell-Morten, Andersen Oluf, Hillert Jan, Sorensen Per Soelberg, Svejgaard Arne, Compston Alastair, Vartdal Frode, Spurkland Anne
Abstract excerpt
We report the first two genome-wide screens for linkage disequilibrium between putative multiple sclerosis (MS) susceptibility genes and genetic markers performed in the genetically homogenous Scandinavian population, using 6000 microsatellite markers and DNA pools of approximately 200 MS cases and 200 controls in each screen. Usable data were achieved from the same 3331 markers in both screens. Nine markers from...
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