Article
Genetic analysis of multiple sclerosis in Europeans: French data.
Journal of neuroimmunology - 1 Oct 2003
Alizadeh Mehdi, Génin Emmanuelle, Babron Marie-Claude, Birebent Brigitte, Cournu-Rebeix Isabelle, Yaouanq Jacqueline, Dréano Stéphane, Sawcer Stephen, Compston Alastair, Clanet Michel, Edan Gilles, Fontaine Bertrand, Clerget-Darpoux Françoise, Semana Gilbert
Abstract excerpt
We report the results of a genome-wide screen for linkage disequilibrium (LD) in multiple sclerosis (MS) performed on 200 cases, 200 controls and 200 case-parent trios from France employing pooled DNA methodology. A total of 3510 microsatellite markers supplied through the GAMES collaborative were analysed and ranked according to their evidence for association. The most promising 117 markers were then followed up...
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