Article
Carboxy-terminal-extended variant of the human fibrinogen .alpha. subunit: a novel exon conferring marked homology to .beta. and .gamma. subunits
8 Dec 1992
Abstract excerpt
Similarities between the N-terminal regions of the three subunits of the clotting protein fibrinogen--(alpha beta gamma)2--suggest that they evolved from a common progenitor. However, to date no human alpha chain has been found with the strong C-terminal homology shared by the beta and gamma chains. Here we examine the natural product of a novel fibrinogen alpha chain transcript bearing a separate open reading...
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