Article
Fibrinogen Hillsborough: a novel gammaGly309Asp dysfibrinogen with impaired clotting.
Blood - 15 May 2002
Mullin Jennifer L, Brennan Stephen O, Ganly Peter S, George Peter M
Abstract excerpt
We present a novel gamma-chain dysfibrinogen that was discovered in a 32-year-old asymptomatic man admitted to the hospital after a car accident. He presented with a low fibrinogen concentration, 0.5 mg/mL, and a prolonged thrombin clotting time, 58 seconds. Analysis of purified fibrinogen by sodium dodecyl sulfate-polyacrylamide gel electrophoresis revealed a gamma-chain variant with an apparently higher...
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