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Article

Extension of the Human Fibrinogen Database with Detailed Clinical Information-The αC-Connector Segment.

International journal of molecular sciences - 23 Dec 2021

Sovova Zofie, Pecankova Klara, Majek Pavel, Suttnar Jiri

Abstract excerpt

Fibrinogen, an abundant plasma glycoprotein, is involved in the final stage of blood coagulation. Decreased fibrinogen levels, which may be caused by mutations, are manifested mainly in bleeding and thrombotic disorders. Clinically relevant mutations of fibrinogen are listed in the Human Fibrinogen Database. For the αC-connector (amino acids Aα240-410, nascent chain numbering), we have extended this database,...

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Identifiers

PMID: 35008554
DOI: 10.3390/ijms23010132
PMCID: PMC8745514

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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