Fib420: a normal human variant of fibrinogen with two extended alpha chains.

doi:10.1073/pnas.91.7.2625

Back to search

Article

Fib420: a normal human variant of fibrinogen with two extended alpha chains.

Proceedings of the National Academy of Sciences of the United States of America - 29 Mar 1994

Fu Y, Grieninger G

Abstract excerpt

In fibrinogen, alpha E chains form a subpopulation of alpha subunits that are distinguished by a carboxyl extension homologous to the C termini of the other two constituent chains: beta and gamma. The molecular mass of alpha E is > 50% greater than that of the common alpha subunit, due in part to...

Topics

Animals
Exons
Fibrinogen
Genetic Variation
Glycosylation
Humans
Models, Molecular
Protein Conformation
Protein Processing, Post-Translational
Recombinant Proteins
Tumor Cells, Cultured
Tunicamycin

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.