Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dominance and overdominance of mildly deleterious induced mutations for fitness traits in Caenorhabditis elegans.

Genetics - 1 Oct 2003

Peters A D, Halligan D L, Whitlock M C, Keightley P D

Abstract excerpt

We estimated the average dominance coefficient of mildly deleterious mutations (h, the proportion by which mutations in the heterozygous state reduce fitness components relative to those in the homozygous state) in the nematode Caenorhabditis elegans. From 56 worm lines that carry mutations induced by the point mutagen ethyl methanesulfonate (EMS), we selected 19 lines that are relatively high in fitness and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans
Share to Ethyl Methanesulfonate
Share to Genes, Dominant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Inbreeding

Share to Mutagens

Share to Mutation

Share to Selection, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 14573472
DOI: 10.1093/genetics/165.2.589
PMCID: PMC1462798

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dominance and overdominance of mildly deleterious induced mutations for fitness traits in Caenorhabditis elegans.PMID 14573472Read ↗

Estimating numbers of EMS-induced mutations affecting life history traits in Caenorhabditis elegans in crosses between inbred sublines.Semantic proximity Read ↗

Low impact of germline transposition on the rate of mildly deleterious mutation in Caenorhabditis elegans.Semantic proximity Read ↗

Properties of ethylmethane sulfonate-induced mutations affecting life-history traits in Caenorhabditis elegans and inferences about bivariate distributions of mutation effects.Semantic proximity Read ↗

On the average coefficient of dominance of deleterious spontaneous mutations.Semantic proximity Read ↗

The fitness effects of spontaneous mutations in Caenorhabditis elegans.Semantic proximity Read ↗

A Genetic Interaction Screening Approach in C. elegans.Semantic proximity Read ↗

Evolution of the rate, molecular spectrum, and fitness effects of mutation under minimal selection in Caenorhabditis elegans.Semantic proximity Read ↗

Genomic mutation rates for lifetime reproductive output and lifespan in Caenorhabditis elegans.Semantic proximity Read ↗

Small fitness effects and weak genetic interactions between deleterious mutations in heterozygous loci of the yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

Selection against males in Caenorhabditis elegans under two mutational treatments.Semantic proximity Read ↗

The effects of spontaneous mutation on quantitative traits. II. Dominance of mutations with effects on life-history traits.Semantic proximity Read ↗

Fitness decline in spontaneous mutation accumulation lines of Caenorhabditis elegans with varying effective population sizes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.