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Article

Hsp90 as a therapeutic target in prostate cancer.

Seminars in oncology - 1 Oct 2003

Solit David B, Scher Howard I, Rosen Neal

Abstract excerpt

Prostate cancers are hormone-dependent malignancies that respond to drugs that reduce circulating testosterone levels or prevent binding of this ligand to the androgen receptor (AR). While effective, these approaches are not curative and, in almost all cases, progression to a castration-resistant state is eventually observed. The mechanisms underlying the development of hormone resistance are poorly defined but...

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PMID: 14571418
DOI: 10.1016/s0093-7754(03)00346-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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