Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Heat shock protein 90

1 Nov 2003

Abstract excerpt

PURPOSE OF REVIEW: Heat shock protein 90 (Hsp90) is a molecular chaperone required for the stability and function of a number of conditionally activated and/or expressed signaling proteins, as well as multiple mutated, chimeric, or overexpressed signaling proteins, which promote cancer cell growth or survival or both. Hsp90 inhibitors, by interacting specifically with a single molecular target, cause the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Healthcare and Venom Research
Share to Heat shock proteins research
Share to Signaling Pathways in Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 14624223
DOI: 10.1097/00001622-200311000-00003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Heat shock protein 90PMID 14624223Read ↗

Using Natural Product Inhibitors to Validate Hsp90 as a Molecular Target in CancerSemantic proximity Read ↗

Heat Shock Proteins Promote Cancer: It's a Protection Racket.Semantic proximity Read ↗

Hsp90: A New Player in DNA Repair?Semantic proximity Read ↗

Heat shock proteins in cancer: chaperones of tumorigenesis.Semantic proximity Read ↗

Co-targeting HSP90 alpha and CDK7 overcomes resistance against HSP90 inhibitors in BCR-ABL1+ leukemia cells.Semantic proximity Read ↗

Clinical significance of heat shock protein 90α in the diagnosis, efficacy and prognosis of breast cancerSemantic proximity Read ↗

Hsp90: A Global Regulator of the Genotype-to-Phenotype Map in Cancers.Semantic proximity Read ↗

Comprehensive pan-cancer analysis of heat shock protein 110, 90, 70 and 60 familiesSemantic proximity Read ↗

Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer.Semantic proximity Read ↗

HSP70 Multi-Functionality in CancerSemantic proximity Read ↗

HSP90 and HSP70: Implication in Inflammation Processes and Therapeutic Approaches for Myeloproliferative NeoplasmsSemantic proximity Read ↗

Redefining the Phenotype of Heat Shock Protein 90 (Hsp90) Inhibitors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.