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Article

Human allelic variation: perspective from protein function, structure, and evolution.

Current opinion in structural biology - 1 Jun 2010

Jordan Daniel M, Ramensky Vasily E, Sunyaev Shamil R

Abstract excerpt

It is widely anticipated that the coming year will be marked by the complete characterization of DNA sequence of protein-coding regions of thousands of human individuals. A number of existing computational methods use comparative protein sequence analysis and analysis of protein structure to predict the functional effect of coding human alleles. Functional and structural analysis of coding allelic variants can...

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Identifiers

PMID: 20399638
DOI: 10.1016/j.sbi.2010.03.006
PMCID: PMC2921592

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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