Article
Synthesis and recognition by DNA polymerases of a reactive nucleoside for DNA diversification.
Nucleosides, nucleotides & nucleic acids - 1 Jan 2000
Pochet S, Dugué L, Strobel H
Abstract excerpt
The synthesis of 1-(2-deoxy-beta-D-erythro-pentofuranosyl)imidazole-4-hydrazide having the features of an ambigous base is reported. The recognition of the analogue by DNA polymerases as an incoming triphosphate as well as a template base was investigated. The mutagenic properties was evaluated b...
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