Article
Whole-genome analysis and HLA genotyping of enteropathy-type T-cell lymphoma reveals 2 distinct lymphoma subtypes.
Gastroenterology - 1 May 2007
Deleeuw Ronald J, Zettl Andreas, Klinker Erdwine, Haralambieva Eugenia, Trottier Magan, Chari Raj, Ge Yong, Gascoyne Randy D, Chott Andreas, Müller-Hermelink Hans-Konrad, Lam Wan L
Abstract excerpt
BACKGROUND & AIMS: Enteropathy-type T-cell lymphoma (ETL) is an aggressive extranodal T-cell non-Hodgkin lymphoma assumed to arise in the setting of celiac disease. METHODS: To precisely define the genetic alterations underlying the pathogenesis of ETL, 30 ETL samples were profiled for genetic copy number alterations using high-resolution whole-genome tiling path array comparative genomic hybridization. To...
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