Article
Glutathione S-transferase M1 and T1 polymorphisms and the risk of recurrent pregnancy loss.
Molecular human reproduction - 1 Mar 2003
Sata F, Yamada H, Kondo T, Gong Y, Tozaki S, Kobashi G, Kato E H, Fujimoto S, Kishi R
Abstract excerpt
The aetiology of recurrent pregnancy loss (RPL) remains unclear, but it may be related to a possible genetic predisposition together with involvement of environmental factors. We examined the relation between RPL and polymorphisms in two genes, glutathione S-transferases (GST) M1 and T1, which are involved in the metabolism of a wide range of environmental toxins and carcinogens. A case-control study of 115 cases...
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