Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Serum levels of alpha1-antitrypsin predict phenotypic expression of the alpha1-antitrypsin gene.

Digestive diseases and sciences - 1 Sept 2003

Steiner Steven J, Gupta Sandeep K, Croffie Joseph M, Fitzgerald Joseph F

Abstract excerpt

We conducted a retrospective analysis to determine if both alpha1-antitrypsin serum level and phenotype need be studied when evaluating children for alpha1-AT deficiency. We collected data from patients less than 19 years old who had both serum alpha1-AT level and phenotype determined over a 9-year period (January 1992-December 2000). Eighty-eight patients were identified and 15 had the PiZZ phenotype. The serum...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to alpha 1-Antitrypsin
Share to alpha 1-Antitrypsin Deficiency

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Infant

Share to Phenotype

Share to Predictive Value of Tests

Source

Identifiers

PMID: 14561003
DOI: 10.1023/a:1025411515683

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Serum levels of alpha1-antitrypsin predict phenotypic expression of the alpha1-antitrypsin gene.PMID 14561003Read ↗

α1-Antitrypsin phenotypes and associated serum protein concentrations in a large clinical population.Semantic proximity Read ↗

Alpha1-antitrypsin deficiency: from genotype to childhood disease.Semantic proximity Read ↗

Alpha 1-antitrypsin deficiency (PiZZ): features of liver involvement in childhood.Semantic proximity Read ↗

Reference and interpretive ranges for α(1)-antitrypsin quantitation by phenotype in adult and pediatric populations.Semantic proximity Read ↗

Use of a highly purified alpha 1-antitrypsin standard to establish ranges for the common normal and deficient alpha 1-antitrypsin phenotypes.Semantic proximity Read ↗

Ongoing research in Europe: Alpha One International Registry (AIR) objectives and development.Semantic proximity Read ↗

Prevalence of α1-antitrypsin deficiency alleles PI*S and PI*Z worldwide and effective screening for each of the five phenotypic classes PI*MS, PI*MZ, PI*SS, PI*SZ, and PI*ZZ: a comprehensive review.Semantic proximity Read ↗

Alpha-1-antitrypsin deficiency in children: liver disease is not reflected by low serum levels of alpha-1-antitrypsin - a study on 48 pediatric patients.Semantic proximity Read ↗

Alpha1-Antitrypsin Deficiency.Semantic proximity Read ↗

Alpha1-Antitrypsin Deficiency.Semantic proximity Read ↗

Alpha-1 antitrypsin Pi*Z gene frequency and Pi*ZZ genotype numbers worldwide: an update.Semantic proximity Read ↗

Alpha1-antitrypsin deficiency. 1: epidemiology of alpha1-antitrypsin deficiency.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.