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Article

Silencing of RNA helicase II/Gualpha inhibits mammalian ribosomal RNA production.

The Journal of biological chemistry - 26 Dec 2003

Henning Dale, So Rolando B, Jin Runyan, Lau Lester F, Valdez Benigno C

Abstract excerpt

The intricate production of ribosomal RNA is well defined in yeast, but its complexity in higher organisms is barely understood. We recently showed that down-regulation of nucleolar protein RNA helicase II/Gualpha (RH-II/Gualpha or DDX21) in Xenopus oocytes inhibited processing of 20 S rRNA to 18 S and contributed to degradation of 28 S rRNA (Yang, H., Zhou, J., Ochs, R. L., Henning, D., Jin, R., and Valdez, B....

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Source

Identifiers

PMID: 14559904
DOI: 10.1074/jbc.M310846200

Genes

DDX21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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