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Article

Estradiol binding to maxi-K channels induces their down-regulation via proteasomal degradation.

The Journal of biological chemistry - 9 Jan 2004

Korovkina Victoria P, Brainard Adam M, Ismail Plabon, Schmidt Thomas J, England Sarah K

Abstract excerpt

Estrogens exert their biological action via both genomic and non-genomic mechanisms. Proteins different from classical estradiol receptors are believed to mediate the latter effects. Here we demonstrate that the maxi-K channel functions as an estrogen-binding protein in transfected HEK293 cells....

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Identifiers

PMID: 14555652
DOI: 10.1074/jbc.M309158200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14555652-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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