Article
Interaction with Tap42 is required for the essential function of Sit4 and type 2A phosphatases.
Molecular biology of the cell - 1 Nov 2003
Wang Huamin, Wang Xiaodong, Jiang Yu
Abstract excerpt
In Saccharomyces cerevisiae, Pph21 and Pph22 are the two catalytic subunits of type 2A phosphatase (PP2Ac), and Sit4 is a major form of 2A-like phosphatase. The function of these phosphatases requires their association with different regulatory subunits. In addition to the conventional regulatory subunits, namely, the A and B subunits for Pph21/22 and the Sap proteins for Sit4, these phosphatases have been found...
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