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Article

Thrombin and phenotypic modulation of the endothelium.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jan 2004

Minami Takashi, Sugiyama Akira, Wu Sheng-Qian, Abid Ruhul, Kodama Tatsuhiko, Aird William C

Abstract excerpt

Thrombin signaling in the endothelium is linked to multiple phenotypic changes, including alterations in permeability, vasomotor tone, and leukocyte trafficking. The thrombin signal is transduced, at least in part, at the level of gene transcription. In this review, we focus on the role of thrombin signaling and transcriptional networks in mediating downstream gene expression and endothelial phenotype. In...

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Identifiers

PMID: 14551154
DOI: 10.1161/01.ATV.0000099880.09014.7D

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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