Article
Integrin-linked kinase is a positive mediator of L6 myoblast differentiation.
Biochemical and biophysical research communications - 24 Oct 2003
Miller Mathew G, Naruszewicz Izabela, Kumar Ashu S, Ramlal Toolsie, Hannigan Gregory E
Abstract excerpt
Overexpression of ILK in L6 myoblasts results in increased ILK kinase activity, stimulating myotube formation and induction of biochemical differentiation markers. Expression of a dominant negative ILK mutant, ILK(E359K), inhibits endogenous ILK activation and L6 differentiation. Cell cycle analy...
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