Article
Pregnancy-associated venous thromboembolism (VTE) in combined heterozygous factor V Leiden (FVL) and prothrombin (FII) 20210 A mutation and in heterozygous FII single gene mutation alone.
British journal of haematology - 1 Oct 2003
Samama Meyer-Michel, Rached Roberto A, Horellou Marie-Hélène, Aquilanti Sandro, Mathieux Valérie G, Plu-Bureau Geneviève, Elalamy Ismail, Conard Jacqueline
Abstract excerpt
The risk of venous thromboembolism (VTE) in the absence of prophylaxis was evaluated in a retrospective study of 47 women (84 pregnancies) with combined thrombophilia [heterozygous factor V Leiden (FVL) plus prothrombin (FII) 20210A mutation (group I)] and in 82 women (193 pregnancies) with the FII alone (group II). VTE was more frequent in group I than in group II [17.8% versus 6.2%, P = 0.003, relative risk...
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