Article
Microfluidic chip-based method for genotyping microsatellites, VNTRs and insertion/deletion polymorphisms.
Clinical biochemistry - 1 Feb 2003
Sohni Youvraj R, Burke James P, Dyck Peter J, O'Kane Dennis J
Abstract excerpt
We have developed a method to genotype variable number of tandem repeats (VNTRs) and insertion/deletion polymorphisms using an integrated microfluidic chip-based system. We used this method to analyze a) a highly polymorphic pentanucleotide repeat (CCTTT)(n) locus within the 5'-putative promoter region of the human inducible nitric oxide synthase gene (iNOS5) which is associated with diabetic complications and...
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