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Article

Stromal-cell derived factor-1 chemokine gene variant is associated with type 1 diabetes age at onset in Japanese population.

Human immunology - 1 Oct 2003

Ide Akane, Kawasaki Eiji, Abiru Norio, Sun Fuyan, Fukushima Tetsuya, Takahashi Ryoko, Kuwahara Hironaga, Fujita Naruhiro, Kita Atsushi, Oshima Katsuya, Uotani Shigeo, Yamasaki Hironori, Yamaguchi Yoshihiko, Kawabata Yumiko, Fujisawa Tomomi, Ikegami Hiroshi, Eguchi Katsumi

Abstract excerpt

Stromal-cell derived factor-1 (SDF-1) is a powerful chemokine that upregulates T-cell migration and activation. The gene for SDF-1 is located near type 1 diabetes susceptibility locus IDDM10, suggesting a contribution by SDF-1 to the induction of diabetes. Recently the role of SDF-1 gene polymorphism in the clinical presentation of type 1 diabetes in French population has been reported. To test the putative...

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Identifiers

PMID: 14522095
DOI: 10.1016/s0198-8859(03)00176-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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