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Article

Age-related changes in the transcriptional profile of mouse RPE/choroid

11 Nov 2003

Abstract excerpt

To evaluate the age-related changes in gene expression occurring in the complex of retinal pigmented epithelium, Bruch's membrane, and choroid (RPE/choroid), we examined the gene expression profiles of young adult (2 mo) and old (24 mo) male C57BL/6 mice. cDNA probe sets from individual animals were synthesized using total RNA isolated from the RPE/choroid of each animal. Probes were amplified using the Clontech...

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PMID: 14519767
DOI: 10.1152/physiolgenomics.00126.2003

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