Article
Lymphocyte regulation of neuropeptide gene expression after neuronal injury.
Journal of neuroscience research - 15 Oct 2003
Armstrong Brian D, Hu Zhongting, Abad Catalina, Yamamoto Miya, Rodriguez Williams I, Cheng Jennifer, Tam Jimmy, Gomariz Rosa P, Patterson Paul H, Waschek James A
Abstract excerpt
The neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylyl cyclase-activating peptide (PACAP) are induced strongly in neurons after several types of injury, and exhibit neuroprotective actions in vitro and in vivo. It is thought that changes in expression of neuropeptides and other molecules in injured neurons are mediated by new factors produced in Schwann and immune cells at the injury site, a...
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