Article
Neuroprotective effect of endogenous pituitary adenylate cyclase-activating polypeptide on spinal cord injury.
Journal of molecular neuroscience : MN - 1 Nov 2012
Tsuchikawa Daisuke, Nakamachi Tomoya, Tsuchida Masashi, Wada Yoshihiro, Hori Motohide, Farkas Jozsef, Yoshikawa Akira, Kagami Nobuyuki, Imai Nori, Shintani Norihito, Hashimoto Hitoshi, Atsumi Takashi, Shioda Seiji
Abstract excerpt
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuroprotective peptide expressed in the central nervous system. To date, changes in the expression and effect of endogenous PACAP have not been clarified with respect to spinal cord injury (SCI). The aim of this study was to elucidate the expression pattern and function of endogenous PACAP on the contusion model of SCI using heterozygous PACAP...
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